SARS-CoV-2 TEST SYSTEMS

The RT-PCR test for COVID-19 is the global standard for diagnosing coronavirus. This is a molecular genetic test that uses a technique to amplify small, SARS-CoV-2-specific DNA fragments. It can be used to determine whether the test material contains genetic material of the virus, even in small quantities. The test is performed on nasopharyngeal and oropharyngeal sample (nasal and throat sample). 

The PCR test is the earliest diagnostic marker for COVID-19. It detects the pathogen in subclinical or asymptomatic forms, even before the virus carrier is able to transmit the infection to others. By extracting the carrier of genetic information (RNA) of the virus and subsequent detection by RT-PCR of several genes, unique and specific for SARS-CoV-2, GENICA Lab delivers results of a PCR test using the highest-class laboratory analysis. GENICA’s RT-PCR test for SARS-CoV-2 meets the high analytical criteria for а genetic laboratory. It detects highly sensitive unique genes, specific only for this virus, guaranteeing the accuracy and precision of the results.

GENICA holds INSTAND E.V. certificate for international quality of laboratory diagnostics for SARS-CoV-2.

COVID-19 antigen assays look for the antigen in the virus envelope protein. These tests are faster than PCR diagnostics but have lower sensitivity and specificity than the PCR test, because they do not multiply the in-vitro viral antigen (as in the PCR method) but detect the actual viral amount in the sample. Due to the lack of viral replication the rapid antigen test is applicable to patients with a high viral load. These tests are a good screening choice for patients with symptoms. The best time for testing is about a week after possible risky contact with a positive patient or during the first week of clinical symptoms. A negative result does not rule out the possibility of COVID-19 infection and should be interpreted in conjunction with the clinical picture, patient history, and epidemiological information. In case of clinical and epidemiological data, regardless of the negative result of the rapid antigen test, PCR must be performed.

COVID-19 antibodies (for certificate) is a laboratory test for quantitative testing of Anti-SARS-CoV2 IgG. Quantitative tests for the detection of antibodies against SARS CoV-2 allow the assessment of the humoral immune response of the body following COVID-19 infection or vaccine, as well as its dynamic follow-up.

A certificate for the presence of antibodies against SARS-CoV-2 is issued after a laboratory proven quantitative test of Anti-SARS-CoV2 IgG with values

greater than 150 BAU / ml. 

The document is created in the National COVID-19 Information System only for persons with laboratory results corresponding to the above, and is available in electronic format on the National Health Information System website - https://his.bg. The certificate is valid for up to 90 days from the date of the laboratory test. 

During a respiratory viral infection, SARS-CoV-2 first infects the cells of the oropharynx and nasopharynx, as the newly formed virus particles are released from the infected cells and enter the salivary secretions. In this way, when a person talks, coughs, sneezes, he/she spreads the virus to the surrounding area, infecting the people around him/her. Following the course of viral infection, saliva stands out as one of the preferred materials for the study of COVID-19.

The PCR saliva test has high sensitivity and specificity. It is non-invasive, completely safe and with zero discomfort for the patient.

Saliva is more sensitive than nasopharyngeal swabs for the diagnosis of asymptomatic and mild COVID-19 infection. It is at least as sensitive as the nasopharyngeal swab in severe COVID-19 infection, according to recent studies published in medical journals.

Saliva PCR test results are recognized worldwide.

This test offers simultaneous testing for COVID-19, influenza A and influenza B with a single sample of nasopharyngeal or oropharyngeal specimen (nasal or throat sample). The technology is the same as in the RT-PCR tests for COVID-19. It differs in that there are several different primer and fluorescent probes specifically targeted at: influenza virus matrix protein type A (Flu A), influenza virus type B matrix protein (Flu B), and nucleocapsid gene N of SARS-CoV-2 virus.

This type of test is recommended by the WHO for the specific diagnosis and differentiation of the three viruses as causes of acute respiratory disorders with similar symptoms but with different causes and different treatments.

This test offers simultaneous testing for COVID-19, influenza A, influenza B and respiratory syncytial virus (RSV) with a single sample of nasopharyngeal or oropharyngeal specimen (nasal or throat sample). The technology is the same as in the RT-PCR tests for COVID-19. It differs in that there are several different primer and fluorescent probes specifically targeted at: influenza virus matrix protein type A (Flu A), influenza virus type B matrix protein (Flu B), RSV and nucleocapsid gene N of SARS-CoV-2 virus.

These types of tests are recommended by the WHO for the specific diagnosis and differentiation of the four viruses as causes of acute respiratory disorders with similar symptoms but with different causes and different treatments.

PCR test for simultaneous detection of 18 pathogens associated with acute respiratory viral infections. It includes testing for the new coronavirus, the two influenza and 15 non-influenza viruses. 

The test detects a number of respiratory viruses associated with influenza and non-influenza respiratory infections, distinguishing them from SARS-CoV-2, that causes COVID-19. In addition to SARS-CoV-2, influenza virus type B and three separate strains of influenza virus type A, the test detects four other coronaviruses, human metapneumovirus, human rhinovirus, adenovirus, bocavirus, parainfluenza virus, respiratory syncytial virus (RSV).

The test results provide information to the physician about the type of pathogen that causes the respiratory disease (viral, bacterial, or mixed etiology). This allows for an informed assessment of the therapeutic approach for the patient - for example, the need for anti-influenza drugs, antibiotics or only symptomatic treatment and more.

This is PCR test for simultaneous detection of 22 pathogens associated with acute respiratory viral infections. It includes testing for the new coronavirus, the two influenza and 19 non-influenza viruses, covering all possible respiratory viral pathogens.

ARVI screen 22® detects a number of respiratory viruses associated with influenza and non-influenza respiratory infections, distinguishing them from SARS-CoV-2, that causes COVID-19. In addition to SARS-CoV-2, influenza virus type B and three separate strains of influenza virus type A, the test detects four other coronaviruses, human metapneumovirus, human rhinovirus, adenovirus, bocavirus, parainfluenza virus, respiratory syncytial virus (RSV), parechovirus and paramyxovirus.

The test results provide information to the physician about the type of pathogen that causes the respiratory disease (viral, bacterial, or mixed etiology). This allows for an informed assessment of the therapeutic approach for the patient - for example, the need for anti-influenza drugs, antibiotics, or only symptomatic treatment and more.