Genetic Testing for Healthy Diet

Genetic panel Healthy Diet and Sport includes an analysis of genetic variants related to the proper absorption of fats and carbohydrates, as well as a person's tendency to benefit from exercising. A recommendation for a nutrition plan and the physical activity needed is made based on these analyses. The persons tested can follow them for proper and healthy absorption of nutrients and for reducing the risk of gaining extra weight.

The DNA Nutri panel includes genetic markers known to be most important for the metabolism of essential macronutrients. Some people may be more sensitive to the amount of fats and carbohydrates they consume, while others may achieve optimal weight loss with a proper nutrition and sports plan. The aim is to achieve long-term results, excluding the negatives of the so-called "Yo-yo effect".

The test results will provide information about:

- Tendency to accumulate fat and extra weight (obesity) 

- Efficiency in fat breakdown

- The use of carbohydrates during to physical activity and stress 

The results will help in determining: 

- Diet (type of diet) - low-carbohydrate, low-lipid, balanced 

- Physical activity - degree of intensity, training program

Genetic panel Metabolism and development provides an individual approach in children with neurological symptoms, autism, developmental problems, metabolic diseases and more. The panel includes analysis of variants located in genes of important metabolic pathways associated with changes in neurotransmitter and methylation cycles, with a predisposition to vitamin, mineral and choline deficiencies, with improper detoxification, and with a risk of histamine intolerance. The panel provides a systematic approach and supports the course of treatment in order to improve the quality of life.

The DNA Nutri Plus panel is an extended version of the DNA Nutri panel and includes genetic markers known to be most important for the metabolism of essential macronutrients as well as those involved in the absorption of important for the body vitamins. The test will also provide information about the need to take additional antioxidants to cleanse the body.

The test results will provide information about: tendency to accumulate fat and extra weight (obesity), efficiency in fat breakdown, the use of carbohydrates during to physical activity and stress, sensitivity to the sodium composition of food, skeletal muscle type, muscle strength and endurance during exercise, absorption of vitamins, and antioxidant capacity and detoxification.

The results will help in determining: 

- Diet (type of diet) - low-carbohydrate, low-lipid, balanced 

- Physical activity - degree of intensity, training program

- Need to take vitamins - B6, B9 (folinic acid), B12 and vitamin D 

- Need to take antioxidants / foods rich in antioxidants 

The DNA Pro panel includes analysis of genetic markers that determine differences in metabolism, lipolysis, and fat absorption. The results are useful in providing an appropriate nutrition and sport plan.

The test results will provide information about: tendency to accumulate fat and extra weight (obesity), efficiency in fat breakdown, sensitivity to the sodium composition of food, skeletal muscle type, muscle strength and endurance during exercise, tendency to recover from injuries.

The results will help in determining: 

- Diet (type of diet) - low-carbohydrate, low-lipid, balanced 

- Physical activity - degree of intensity, training program

- Risk of sports injuries

The DNA Sport panel includes genetic markers providing information for preparing a highly effective personalized training program. It will help you avoid the negatives and the waste of time from the trial-and-error approach.

The test results will provide information about: your skeletal muscle type, muscle strength and endurance during exercise, sensitivity to the sodium composition of food, heart rate and blood pressure regulation, risk of muscle inflammation and tendency to break down and accumulate fat.

The results will help in determining: 

- Physical activity - type, duration, intensity, and frequency of the exercises practiced

- Diet (type of diet) - low-carbohydrate, low-lipid, balanced 

The DNA Sport Plus is an extended version of the DNA Sport Panel and includes analysis of genetic markers providing information for preparing a highly effective personalized training program. It is suitable for people who like physical exercise and want to achieve the best results, as well as for people who do sports professionally.

The test results will provide information about: your skeletal muscle type, muscle strength and endurance during exercise, tendency to gain muscle mass, risk of muscle inflammation, heart rate and blood pressure regulation, sensitivity to the sodium composition of food, tendency to break down and accumulate fat and hormonal balance.

The results will help in determining: 

- Physical activity - type, duration, intensity, and frequency of the exercises practiced

- Risk of sports injuries and inflammations

- Diet (type of diet) - low-carbohydrate, low-lipid, balanced 

- Testosterone production (in men)

The DNA SportFit - All in one panel is a complete package of genetic markers, providing information about the individual response to a certain lifestyle, including an appropriate nutrition and exercise plan, as well as the need for supplementation. Based on the obtained results, personalized programs for prevention, nutrition and training are developed.

The test results will provide information about:: tendency to accumulate fat and extra weight (obesity), efficiency in breaking down fat, absorption of carbohydrates in response to physical activity and stress, type of skeletal muscle, muscle strength and endurance during exercise, tendency to accumulate muscle mass, risk of muscle inflammation, heart rate and blood pressure regulation, sensitivity to the sodium composition of food, absorption of vitamins, hormonal balance, antioxidant capacity and detoxification and lactose intolerance.

The results will help in determining:

- Diet - (type of diet) low-carbohydrate, low-lipid, balanced; tolerance to foods high in sodium content

- Training plan - type, duration, intensity and frequency of practiced exercises, the need for training under hypoxia and the appropriate type of cardio training

- Risk of sports injuries and inflammations

- Testosterone production (in men)

 - Need to take vitamins - A, B6, B9 (folic acid), B12 and vitamin D

- Need to take antioxidants / foods rich in antioxidants

- Individual lactate threshold (tendency to accumulate lactic acid)

Vitamins play a key role in the proper performance of basic functions of the human body such as metabolism, immune defense, activity of the central and peripheral nervous systems, digestion, movement etc. Most vitamins are not synthesized in the human body but are taken with food as precursors of their active forms. Therefore, their proper absorption, transformation, use, and decomposition is important for maintaining the so-called vitamin balance.

The Vitamins Genetics Panel includes an analysis of genetic variants associated with predisposition to vitamin A, B, D, and K deficiencies. The results contain interpretation, clinical significance of proven variants, and recommendations that assist practitioners in making therapeutic decisions. Each patient receives guidelines for changing their diet, as well as for taking specific vitamins and minerals.

Vitamin B6 is an important factor in the formation of the red blood cells, the developing of nervous tissue, the detoxification processes, the DNA synthesis, the cell energy balance and the immune protection. It is also a key factor in the methylation processes that regulate the "unlocking" or "locking" of our genes. Methylation disorders can lead to elevated homocysteine levels, which are associated with a large number of diseases.

Vitamin B6 Genetic Panel includes analysis of genetic variants associated with faster degradation of vitamin B6 and systemically low bioavailability of its active form, called Pyridoxal-5-phosphate. The results contain interpretation, clinical significance of identified variants and recommendations to assist specialists in making therapeutic decisions.

Vitamin B12 is supplied only with food. It is a key factor in to the functioning of vital body processes, including the formation of red blood cells, DNA synthesis, normal nervous system function, digestion. If Vitamin B12 deficiency is not managed in time, it can lead to anemia, a number of gastrointestinal, neurological, oncological, and other diseases.

Vitamin B12 Genetic Panel includes analysis of genetic variants associated with disorders in the absorption of the vitamin in the small intestine, reduced transport to the liver and faster depletion of its active form.

The results contain interpretation, clinical significance of identified variants and recommendations to assist specialists in making therapeutic decisions.

Vitamin C (ascorbic acid) is not produced in the human body, so we must constantly get it through a balanced diet. It is extremely important because it has numerous functions - improves the absorption of iron in the intestine, protects against free radicals in the body, reduces oxidative damage to DNA and oxidation of LDL cholesterol, etc. Find out if you need to take it in larger doses or not.

Vitamin D is important for the absorption of calcium, which is useful for maintaining good bone health. Exposure to sunlight is an determining factor of vitamin D levels, as there are few natural dietary sources of this vitamin. 

However, genetic changes have been found associated with decreased levels of the major circulating form of vitamin D (hydroxy vitamin D). Also, changes have been found in the vitamin receptor have been found. They disrupt Vitamin D specific binding and would lead to impaired regulation of dopamine levels, and hence to seasonal depression.

Vitamin A is a fat-soluble vitamin extremely important for vision, skin, teeth, bones, and tissues. A key enzyme involved in the beta-carotene metabolism of vitamin A works in the body. It is needed during lifespan as it is involved in reproduction, embryonic development, growth, cell differentiation and proliferation, lipid metabolism and tissue integrity. Vitamin A Genetic Panel includes analysis of genetic variants leading to up to 70% reduced enzyme activity.

The most common symptom of vitamin A deficiency is associated with changes in vision, as well as various diseases such as asthma and cardiovascular disorders.

Vitamin K is an essential cofactor for the normal production of large number of clotting factors, involved in blood clotting processes. It is needed in small and controlled quantities. Vitamin K deficiencies lead to increased bleeding and easy bruising of the tissue. There is evidence of its role in maintaining bone strength. Decreased vitamin levels may be associated with low bone density and an increased risk of fractures.

Nutri Ultra Genetic Panel is applied in setting up personalized nutrition and food supplements plan. The panel is for healthy people to improve their quality of life, as well as for patients diagnosed with metabolic, endocrine, cardiovascular, neurodegenerative, psychiatric, and other disorders.

The panel includes an analysis of variants in genes on important metabolic pathways associated with:

• predisposition to reduced motivation and concentration

• impaired absorption and deficiencies of vitamins, trace elements, choline

• impaired methylation cycle

• reduced body detoxification 

• high levels of homocysteine

• increased levels of blood pressure and LDL-cholesterol

• reduced bone strength and density

A wide range of foods are naturally rich in histamine or release high levels of histamine during storage. Diamine oxidase (DAO) is an intestinal enzyme that normally destroys histamine contained in food. Therefore, even after consuming foods rich in histamine, no symptoms are observed. In carriers of genetic variants, DAO deficiency is observed, and undigested histamine is unnecessarily absorbed, exhibiting various symptoms.

Gastrointestinal symptoms: diarrhea, irritable bowel syndrome (IBS), chronic constipation, gas, stomach pain, vomiting.

Symptoms affecting the head and face: redness of the face and / or chest (a very common symptom), migraine-like headache, Quincke's edema (swelling that occurs mainly around the eyes and lips, sometimes in the throat).

Respiratory problems: asthma, stuffy nose and watery eyes.

Skin complaints: rash, eczema, urticaria, acne.

In women: dysmenorrhea. The symptoms of HIT disappear during pregnancy and return after birth.

Other symptoms: wheezing, sleep disorders, arrhythmia, mood swings - from fatigue to irritability and aggression.

Hereditary fructose intolerance (HFI) is an autosomal recessive disorder where fructose metabolism is impaired. It results from a deficiency of the enzyme aldolase B. HFI is caused by mutations in the ALDOB gene (9q22.3) resulting in reduced enzyme function. Affected individuals are asymptomatic until they start taking fructose, sucrose, or sorbitol.

HFI should not be confused with a condition called fructose malabsorption. In it, the intestinal cells cannot normally absorb fructose, which leads to bloating, diarrhea or constipation, flatulence, and abdominal pain.

The test is needed if fructose intolerance is suspected. Genetic analysis makes it possible to avoid invasive liver biopsy by detecting at-risk patients carrying a specific mutation.

Celiac disease is an autoimmune disease occurring in genetically predisposed people of different ages. It is due to intolerance to gluten and other similar proteins contained in wheat, rye, oats and barley. As a result, chronic inflammation, atrophy of the villis and thinning of the lining of the small intestine occur.

In patients with a predisposition to celiac disease (high and medium risk), it may be triggered by surgery, pregnancy, viral infections (with rota- and adenoviruses), stressful situations, etc.

The test is prescribed when celiac disease is suspected and positive immunological markers for this disease exist. Genetic analysis makes it possible to detect patients at risk without performing an invasive small bowel biopsy.

The test is an analysis of a genetic variant affecting the production of the enzyme lactase, encoded by the LCT gene. This enzyme is responsible for the lactose breakdown and its reduced function leads to impaired breakdown and absorption of the lactose in milk. The increased risk of lowered lactase function leads to a risk of developing lactose intolerance and the need to reduce the intake of milk and dairy products.

Folate (Vitamin B9) is part of the B vitamins group and is associated with the normal development of the fetus during pregnancy, the formation of red blood cells, proper DNA synthesis, methylation, and detoxification of the cell.

The Folate genetic test involves the analysis of genetic variants in the MTHFR gene associated with the proper absorption of folic acid and a possible risk of vitamin deficiency, which is often accompanied by an increase in homocysteine levels. The test is used to determine the need for additional folic acid intake in order to improve the quality of life in people of different ages.

Serotonin is known as an inhibitory neurotransmitter and as a precursor to melatonin. In the central nervous system, it has a mood-lifting, relaxing and antidepressant effect. It supports learning and memory. Peripherally, serotonin plays a role in blood clotting (platelets) and wound healing. Serotonin is also very important for the intestines as it affects peristalsis, resorption and immune activity. 95% of serotonin is formed in the intestines. Appetite control depends on it: high levels of serotonin promote a feeling of satiety, while low levels are characterized by increased feeling of hunger and can lead to eating disorders.

Genetic changes are associated with an increased risk of choline deficiency. This may increase the risk of developing fatty liver and liver disease.

Find out if you need iron or if you are overloaded with iron. Iron deficiency is observed when the amount of iron after depletion of reserves is not sufficient to cover functional needs, or when there is insufficient release of iron from reserves as a result of genetic modification.